Orthonome is a novel orthology prediction pipeline and database developed to be robust to current challenges posed by draft assemblies.

Leveraging a thorough identification of inparalogues (gene duplications) and orphan genes (gene births) - Orthonome is able to predict orthogonal orthology relationships between species with higher recall and reduced error (in review).

Currently implemented: 20 Drosophila species .. and increasing!

What makes Orthonome so cool?

Improved accuracy

Greater concordance with species trees. Gets you orthologues closest to ground truth!

Greater recall

Orthonome is able to deliver a greater number of orthologous relationships between species without compromising on quality!.

More robust when using non-model species genomes!

Orthonome has been designed to correct for errors introduced by incomplete assemblies, annotations or fragmented genes - giving more robust and replicable results!